IRS-1 (phospho Ser616) rabbit pAb

Sizes: 50μL, 100μL

Catalogue Numbers: ES5927-50, ES5927-100

Citations, Manuals and MSDS Available upon request.

Background: This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],

Alternate Name: IRS1; Insulin receptor substrate 1; IRS-1

Source: Rabbit

Applications: WB; IHC; IF; ELISA

Dilution: Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

Reactivity: Human; Mouse; Rat

Immunogen: The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser612. AA range:578-627

Storage and Stability: -20°C/1 year

Clonality: Polyclonal

Isotype: IgG

Concentration: 1 mg/ml

Observed Band (KD): 170kD

Human Gene ID: 3667

Human SWISS Prot NO: P35568

Subcellular Location: nucleus, cytoplasm, cytosol, plasma membrane, insulin receptor complex, caveola, intracellular membrane-bounded organelle,

Research Use Only