NAN-190 hydrobromide is a serotonin receptor 5-HT antagonist. NAN-190 is a selective antagonist of 5-HT1A.

Product information

CAS Number: 115338-32-4

Molecular Weight: 474.39

Formula: C23H28BrN3O3

Chemical Name: 2-{4-[4-(2-methoxyphenyl)piperazin-1-yl]butyl}-2,3-dihydro-1H-isoindole-1,3-dione hydrobromide

Smiles: Br.COC1=CC=CC=C1N1CCN(CCCCN2C(=O)C3=CC=CC=C3C2=O)CC1

InChiKey: AXRUEPFPTQYHQD-UHFFFAOYSA-N

InChi: InChI=1S/C23H27N3O3.BrH/c1-29-21-11-5-4-10-20(21)25-16-14-24(15-17-25)12-6-7-13-26-22(27)18-8-2-3-9-19(18)23(26)28;/h2-5,8-11H,6-7,12-17H2,1H3;1H

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Solubility: DMSO : 16.67 mg/mL (35.14 mM; Need ultrasonic).

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vivo:

NAN-190 hydrobromide (0.5 mg/kg, ip) is injected concomitantly with the effective dose of fluoxetine. NAN-190 reverses the catalepsy-improving effect of fluoxetine in 6-OHDA lesioned rats.

Products are for research use only. Not for human use.