ATTENTION
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Please read "Drug Information" before purchase.

Active ingredient
Sitagliptin phosphate hydrate
Brand name medicine
JANUVIA 
Effects of this medicine
・This medicine inhibits enzyme that degrades incretin, blood glucose stabilizing substance. It consequently enhances insulinotropic action and effect of lowering glucagon level in state of hyperglycemia to improve blood glucose control.
・It is usually used to treat type 2 diabetes.
Dosing schedule (How to take this medicine)
・For patients with normal renal function or mild renal dysfunction : In general, for adults, take 2 tablets (50 mg of sitagliptin) at a time, once a day. If the dose seems to be insufficient, it may be increased up to 4 tablets (100 mg) at a time, once a day, adequately monitoring the condition.
・For patients with moderate renal dysfunction : In general, for adults, take 1 tablet (25 mg of sitagliptin) at a time, once a day. If the dose seems to be insufficient, it may be increased up to 2 tablets (50 mg) at a time, once a day, adequately monitoring the condition.
・For patients with severe or end stage renal dysfunction : In general, for adults, take 12.5 mg of sitagliptin at a time, once a day. If the dose seems to be insufficient, it may be increased up to 1 tablet (25 mg) at a time, once a day, adequately monitoring the condition.
・In either case, strictly follow the instructions.
・If you miss a dose, take the missed dose as soon as possible. If it is almost time for the next dose, skip the missed dose and continue your regular dosing schedule. You should never take two doses at one time.
Before using this medicine, be sure to tell your doctor and pharmacist
・If you have previously experienced any allergic reactions (itch, rash, etc.) to any medicines or foods.
・If you have: ketosis, diabetic coma or precoma stage, type 1 diabetes, infection, injury, renal dysfunction, pituitary gland disorder, adrenal gland disorder, insufficient diet, a history of abdominal surgery or intestinal obstruction.
・If you are in pre/postoperative period or debilitated.
・If you exercise intensely or drink a lot of alcohol.
・If you are pregnant or breastfeeding.
・If you are taking any other medicinal products. (Some medicines may interact to enhance or diminish medicinal effects. Beware of over-the-counter medicines and dietary supplements as well as other prescription medicines.)
Precautions while taking this medicine
・Strictly follow diet and exercise therapy instructed by your doctor.
・The medicine may cause hypoglycemic symptoms. Pay attention when you work at heights, drive a car or operate dangerous machinery.
・In case hypoglycemic symptoms occurs, take food or drink that contains enough amount of sugar (sugar, glucose, refreshing drink, etc.).If you are taking the medicine concomitantly with an α-glucosidase inhibitor (medicines which delay absorption of sugar), ingest glucose in case of any hypoglycemic symptoms occur.
・For healthcare professional use only
Storage conditions and other information
・Keep out the reach of children. Store away from direct sunlight, heat and moisture.
・Discard the remainder. Do not store them.